Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity

Rakesh Das; Subhendu Chatterjee

doi:doi:10.11648/j.nano.20170506.13

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Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity

Rakesh Das, Subhendu Chatterjee

Published in American Journal of Nano Research and Applications (Volume 5, Issue 6)

Received: 15 October 2017 Accepted: 25 October 2017 Published: 22 December 2017

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Abstract

Ongoing through all the applications of nano medicines through various sources, it has been understand that preparation of polymeric nanoparticle, liposomes, Dendrimers, Solid Lipid Nanoparticle (SLN) and polymeric micelles is useful for Drug delivery system. Also, helpful to repairs the DNA and treatment of many diseases by increase rate of toxin elimination. The nano medicines in various way initiate the proper biotransformation in livers and also give rise to effective pharmacodynamics profiles. It has been discovered that many nano molecules can be converted into picomolecular medicinal dust (pMMD) entities on lowering the molecular weight, reducing the bond length and shortening the molecular length. This (pMMD) is basically useful in respiratory system treatment, Skin targeted penetration and ophthalmic disorders ramification to ensure hypothetical probability to facilitate Pico-molecular dust involvement as medicinal propeller. Because, it acquires the finest position to receptors less than nano receptors, nano enzymes, nano amino acids chain/polymers, nano pores, nano-microelements, DNA and other nano bio-molecules etc., where nano molecular modules are not effectives. The pico dust will acquires its position into the more specified pico-receptors where nano molecules cannot penetrate or lodge. Pico medicine spray could be implicated superficially over the skin surface at high pressure. So, that it get penetrate upto the subcutaneous and intradermal skin layers with 100% inoculation easily. In ophthalmic preparation, the pico-molecular drugs spray will help to open the drainage area stimulating the receptor on the iris edge corner for dilation of path openings and constriction of circular muscles of eye to create pressure for fluid ejaculation.

Published in	American Journal of Nano Research and Applications (Volume 5, Issue 6)
DOI	10.11648/j.nano.20170506.13
Page(s)	91-101
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Nano-Molecular Medicines, Pico-Molecular Medicinal Dust, High Pressure Propeller, Respiratory Treatment, Skin and Ophthalmic Remedies

References

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APA Style

Rakesh Das, Subhendu Chatterjee. (2017). Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity. American Journal of Nano Research and Applications, 5(6), 91-101. https://doi.org/10.11648/j.nano.20170506.13

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ACS Style

Rakesh Das; Subhendu Chatterjee. Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity. Am. J. Nano Res. Appl. 2017, 5(6), 91-101. doi: 10.11648/j.nano.20170506.13

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AMA Style

Rakesh Das, Subhendu Chatterjee. Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity. Am J Nano Res Appl. 2017;5(6):91-101. doi: 10.11648/j.nano.20170506.13

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@article{10.11648/j.nano.20170506.13,
  author = {Rakesh Das and Subhendu Chatterjee},
  title = {Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity},
  journal = {American Journal of Nano Research and Applications},
  volume = {5},
  number = {6},
  pages = {91-101},
  doi = {10.11648/j.nano.20170506.13},
  url = {https://doi.org/10.11648/j.nano.20170506.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.nano.20170506.13},
  abstract = {Ongoing through all the applications of nano medicines through various sources, it has been understand that preparation of polymeric nanoparticle, liposomes, Dendrimers, Solid Lipid Nanoparticle (SLN) and polymeric micelles is useful for Drug delivery system. Also, helpful to repairs the DNA and treatment of many diseases by increase rate of toxin elimination. The nano medicines in various way initiate the proper biotransformation in livers and also give rise to effective pharmacodynamics profiles. It has been discovered that many nano molecules can be converted into picomolecular medicinal dust (pMMD) entities on lowering the molecular weight, reducing the bond length and shortening the molecular length. This (pMMD) is basically useful in respiratory system treatment, Skin targeted penetration and ophthalmic disorders ramification to ensure hypothetical probability to facilitate Pico-molecular dust involvement as medicinal propeller. Because, it acquires the finest position to receptors less than nano receptors, nano enzymes, nano amino acids chain/polymers, nano pores, nano-microelements, DNA and other nano bio-molecules etc., where nano molecular modules are not effectives. The pico dust will acquires its position into the more specified pico-receptors where nano molecules cannot penetrate or lodge. Pico medicine spray could be implicated superficially over the skin surface at high pressure. So, that it get penetrate upto the subcutaneous and intradermal skin layers with 100% inoculation easily. In ophthalmic preparation, the pico-molecular drugs spray will help to open the drainage area stimulating the receptor on the iris edge corner for dilation of path openings and constriction of circular muscles of eye to create pressure for fluid ejaculation.},
 year = {2017}
}

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TY  - JOUR
T1  - Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity
AU  - Rakesh Das
AU  - Subhendu Chatterjee
Y1  - 2017/12/22
PY  - 2017
N1  - https://doi.org/10.11648/j.nano.20170506.13
DO  - 10.11648/j.nano.20170506.13
T2  - American Journal of Nano Research and Applications
JF  - American Journal of Nano Research and Applications
JO  - American Journal of Nano Research and Applications
SP  - 91
EP  - 101
PB  - Science Publishing Group
SN  - 2575-3738
UR  - https://doi.org/10.11648/j.nano.20170506.13
AB  - Ongoing through all the applications of nano medicines through various sources, it has been understand that preparation of polymeric nanoparticle, liposomes, Dendrimers, Solid Lipid Nanoparticle (SLN) and polymeric micelles is useful for Drug delivery system. Also, helpful to repairs the DNA and treatment of many diseases by increase rate of toxin elimination. The nano medicines in various way initiate the proper biotransformation in livers and also give rise to effective pharmacodynamics profiles. It has been discovered that many nano molecules can be converted into picomolecular medicinal dust (pMMD) entities on lowering the molecular weight, reducing the bond length and shortening the molecular length. This (pMMD) is basically useful in respiratory system treatment, Skin targeted penetration and ophthalmic disorders ramification to ensure hypothetical probability to facilitate Pico-molecular dust involvement as medicinal propeller. Because, it acquires the finest position to receptors less than nano receptors, nano enzymes, nano amino acids chain/polymers, nano pores, nano-microelements, DNA and other nano bio-molecules etc., where nano molecular modules are not effectives. The pico dust will acquires its position into the more specified pico-receptors where nano molecules cannot penetrate or lodge. Pico medicine spray could be implicated superficially over the skin surface at high pressure. So, that it get penetrate upto the subcutaneous and intradermal skin layers with 100% inoculation easily. In ophthalmic preparation, the pico-molecular drugs spray will help to open the drainage area stimulating the receptor on the iris edge corner for dilation of path openings and constriction of circular muscles of eye to create pressure for fluid ejaculation.
VL  - 5
IS  - 6
ER  -

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Author Information

Rakesh Das

Department of Pharmaceutical Technology, Bioequivalence Study Center, Jadavpur University, Kolkata, India
Subhendu Chatterjee

Department of Biotechnology, IIT Karagpur, Kharagpur, WB, India

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APA Style

Rakesh Das, Subhendu Chatterjee. (2017). Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity. American Journal of Nano Research and Applications, 5(6), 91-101. https://doi.org/10.11648/j.nano.20170506.13

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ACS Style

Rakesh Das; Subhendu Chatterjee. Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity. Am. J. Nano Res. Appl. 2017, 5(6), 91-101. doi: 10.11648/j.nano.20170506.13

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AMA Style

Rakesh Das, Subhendu Chatterjee. Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity. Am J Nano Res Appl. 2017;5(6):91-101. doi: 10.11648/j.nano.20170506.13

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@article{10.11648/j.nano.20170506.13,
  author = {Rakesh Das and Subhendu Chatterjee},
  title = {Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity},
  journal = {American Journal of Nano Research and Applications},
  volume = {5},
  number = {6},
  pages = {91-101},
  doi = {10.11648/j.nano.20170506.13},
  url = {https://doi.org/10.11648/j.nano.20170506.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.nano.20170506.13},
  abstract = {Ongoing through all the applications of nano medicines through various sources, it has been understand that preparation of polymeric nanoparticle, liposomes, Dendrimers, Solid Lipid Nanoparticle (SLN) and polymeric micelles is useful for Drug delivery system. Also, helpful to repairs the DNA and treatment of many diseases by increase rate of toxin elimination. The nano medicines in various way initiate the proper biotransformation in livers and also give rise to effective pharmacodynamics profiles. It has been discovered that many nano molecules can be converted into picomolecular medicinal dust (pMMD) entities on lowering the molecular weight, reducing the bond length and shortening the molecular length. This (pMMD) is basically useful in respiratory system treatment, Skin targeted penetration and ophthalmic disorders ramification to ensure hypothetical probability to facilitate Pico-molecular dust involvement as medicinal propeller. Because, it acquires the finest position to receptors less than nano receptors, nano enzymes, nano amino acids chain/polymers, nano pores, nano-microelements, DNA and other nano bio-molecules etc., where nano molecular modules are not effectives. The pico dust will acquires its position into the more specified pico-receptors where nano molecules cannot penetrate or lodge. Pico medicine spray could be implicated superficially over the skin surface at high pressure. So, that it get penetrate upto the subcutaneous and intradermal skin layers with 100% inoculation easily. In ophthalmic preparation, the pico-molecular drugs spray will help to open the drainage area stimulating the receptor on the iris edge corner for dilation of path openings and constriction of circular muscles of eye to create pressure for fluid ejaculation.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity
AU  - Rakesh Das
AU  - Subhendu Chatterjee
Y1  - 2017/12/22
PY  - 2017
N1  - https://doi.org/10.11648/j.nano.20170506.13
DO  - 10.11648/j.nano.20170506.13
T2  - American Journal of Nano Research and Applications
JF  - American Journal of Nano Research and Applications
JO  - American Journal of Nano Research and Applications
SP  - 91
EP  - 101
PB  - Science Publishing Group
SN  - 2575-3738
UR  - https://doi.org/10.11648/j.nano.20170506.13
AB  - Ongoing through all the applications of nano medicines through various sources, it has been understand that preparation of polymeric nanoparticle, liposomes, Dendrimers, Solid Lipid Nanoparticle (SLN) and polymeric micelles is useful for Drug delivery system. Also, helpful to repairs the DNA and treatment of many diseases by increase rate of toxin elimination. The nano medicines in various way initiate the proper biotransformation in livers and also give rise to effective pharmacodynamics profiles. It has been discovered that many nano molecules can be converted into picomolecular medicinal dust (pMMD) entities on lowering the molecular weight, reducing the bond length and shortening the molecular length. This (pMMD) is basically useful in respiratory system treatment, Skin targeted penetration and ophthalmic disorders ramification to ensure hypothetical probability to facilitate Pico-molecular dust involvement as medicinal propeller. Because, it acquires the finest position to receptors less than nano receptors, nano enzymes, nano amino acids chain/polymers, nano pores, nano-microelements, DNA and other nano bio-molecules etc., where nano molecular modules are not effectives. The pico dust will acquires its position into the more specified pico-receptors where nano molecules cannot penetrate or lodge. Pico medicine spray could be implicated superficially over the skin surface at high pressure. So, that it get penetrate upto the subcutaneous and intradermal skin layers with 100% inoculation easily. In ophthalmic preparation, the pico-molecular drugs spray will help to open the drainage area stimulating the receptor on the iris edge corner for dilation of path openings and constriction of circular muscles of eye to create pressure for fluid ejaculation.
VL  - 5
IS  - 6
ER  -

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