Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior

Magdy Abdullah Sayedelahl; Naser Nagib Nasr; Mahmoud Hamed Akr; Dina Sayed Sheha; Tahany Mohamed Rabie

doi:doi:10.11648/j.iji.20150303.13

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Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior

Magdy Abdullah Sayedelahl, Naser Nagib Nasr, Mahmoud Hamed Akr, Dina Sayed Sheha, Tahany Mohamed Rabie

Published in International Journal of Immunology (Volume 3, Issue 3)

Received: 8 June 2015 Accepted: 18 June 2015 Published: 2 July 2015

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Abstract

Background: A randomized single-blinded study including 50 patients with allergic rhinitis. Objective: To evaluate and compare the efficacy of subcutaneous versus sublingual immunotherapy in treatment of allergic rhinitis. Materials and methods: Patients divided into Group A: twenty patients received subcutaneous immunotherapy and group B: twenty patients received sublingual immunotherapy for twelve months. We assessed skin prick test, symptom score and medication use, quality of life and nasal smear eosinophilic count before and after treatment. Results: In group A, clinical improvement was achieved in 100% of monosensitised and 62.5% of polysensitised patients, while in group B 100% of monosensitised and 60% of of polysensitised patients exhibited clinical improvement. Conclusion: The subcutaneous and sublingual routes of immunotherapy have similar efficacy.

Published in	International Journal of Immunology (Volume 3, Issue 3)
DOI	10.11648/j.iji.20150303.13
Page(s)	42-46
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Allergen Specific Immunotherapy, SCIT, SLIT, Allergic Rhinitis, Skin Prick Test, Nasal Smear Eosinophilia, Clinical Improvement

References

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APA Style

Magdy Abdullah Sayedelahl, Naser Nagib Nasr, Mahmoud Hamed Akr, Dina Sayed Sheha, Tahany Mohamed Rabie. (2015). Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior. International Journal of Immunology, 3(3), 42-46. https://doi.org/10.11648/j.iji.20150303.13

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ACS Style

Magdy Abdullah Sayedelahl; Naser Nagib Nasr; Mahmoud Hamed Akr; Dina Sayed Sheha; Tahany Mohamed Rabie. Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior. Int. J. Immunol. 2015, 3(3), 42-46. doi: 10.11648/j.iji.20150303.13

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AMA Style

Magdy Abdullah Sayedelahl, Naser Nagib Nasr, Mahmoud Hamed Akr, Dina Sayed Sheha, Tahany Mohamed Rabie. Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior. Int J Immunol. 2015;3(3):42-46. doi: 10.11648/j.iji.20150303.13

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@article{10.11648/j.iji.20150303.13,
  author = {Magdy Abdullah Sayedelahl and Naser Nagib Nasr and Mahmoud Hamed Akr and Dina Sayed Sheha and Tahany Mohamed Rabie},
  title = {Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior},
  journal = {International Journal of Immunology},
  volume = {3},
  number = {3},
  pages = {42-46},
  doi = {10.11648/j.iji.20150303.13},
  url = {https://doi.org/10.11648/j.iji.20150303.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20150303.13},
  abstract = {Background: A randomized single-blinded study including 50 patients with allergic rhinitis. Objective: To evaluate and compare the efficacy of subcutaneous versus sublingual immunotherapy in treatment of allergic rhinitis. Materials and methods: Patients divided into Group A: twenty patients received subcutaneous immunotherapy and group B: twenty patients received sublingual immunotherapy for twelve months. We assessed skin prick test, symptom score and medication use, quality of life and nasal smear eosinophilic count before and after treatment. Results: In group A, clinical improvement was achieved in 100% of monosensitised and 62.5% of polysensitised patients, while in group B 100% of monosensitised and 60% of of polysensitised patients exhibited clinical improvement. Conclusion: The subcutaneous and sublingual routes of immunotherapy have similar efficacy.},
 year = {2015}
}

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TY  - JOUR
T1  - Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior
AU  - Magdy Abdullah Sayedelahl
AU  - Naser Nagib Nasr
AU  - Mahmoud Hamed Akr
AU  - Dina Sayed Sheha
AU  - Tahany Mohamed Rabie
Y1  - 2015/07/02
PY  - 2015
N1  - https://doi.org/10.11648/j.iji.20150303.13
DO  - 10.11648/j.iji.20150303.13
T2  - International Journal of Immunology
JF  - International Journal of Immunology
JO  - International Journal of Immunology
SP  - 42
EP  - 46
PB  - Science Publishing Group
SN  - 2329-1753
UR  - https://doi.org/10.11648/j.iji.20150303.13
AB  - Background: A randomized single-blinded study including 50 patients with allergic rhinitis. Objective: To evaluate and compare the efficacy of subcutaneous versus sublingual immunotherapy in treatment of allergic rhinitis. Materials and methods: Patients divided into Group A: twenty patients received subcutaneous immunotherapy and group B: twenty patients received sublingual immunotherapy for twelve months. We assessed skin prick test, symptom score and medication use, quality of life and nasal smear eosinophilic count before and after treatment. Results: In group A, clinical improvement was achieved in 100% of monosensitised and 62.5% of polysensitised patients, while in group B 100% of monosensitised and 60% of of polysensitised patients exhibited clinical improvement. Conclusion: The subcutaneous and sublingual routes of immunotherapy have similar efficacy.
VL  - 3
IS  - 3
ER  -

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Author Information

Magdy Abdullah Sayedelahl

Department of Otorhinolaryngology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Naser Nagib Nasr

Department of Otorhinolaryngology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Mahmoud Hamed Akr

Department of Otorhinolaryngology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Dina Sayed Sheha

Department of Internal Medicine, Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Tahany Mohamed Rabie

Department of Otorhinolaryngology, Faculty of Medicine, Ain Shams University, Cairo, Egypt

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Plain Text BibTeX RIS

APA Style

Magdy Abdullah Sayedelahl, Naser Nagib Nasr, Mahmoud Hamed Akr, Dina Sayed Sheha, Tahany Mohamed Rabie. (2015). Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior. International Journal of Immunology, 3(3), 42-46. https://doi.org/10.11648/j.iji.20150303.13

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ACS Style

Magdy Abdullah Sayedelahl; Naser Nagib Nasr; Mahmoud Hamed Akr; Dina Sayed Sheha; Tahany Mohamed Rabie. Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior. Int. J. Immunol. 2015, 3(3), 42-46. doi: 10.11648/j.iji.20150303.13

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AMA Style

Magdy Abdullah Sayedelahl, Naser Nagib Nasr, Mahmoud Hamed Akr, Dina Sayed Sheha, Tahany Mohamed Rabie. Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior. Int J Immunol. 2015;3(3):42-46. doi: 10.11648/j.iji.20150303.13

Copy | Download

@article{10.11648/j.iji.20150303.13,
  author = {Magdy Abdullah Sayedelahl and Naser Nagib Nasr and Mahmoud Hamed Akr and Dina Sayed Sheha and Tahany Mohamed Rabie},
  title = {Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior},
  journal = {International Journal of Immunology},
  volume = {3},
  number = {3},
  pages = {42-46},
  doi = {10.11648/j.iji.20150303.13},
  url = {https://doi.org/10.11648/j.iji.20150303.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20150303.13},
  abstract = {Background: A randomized single-blinded study including 50 patients with allergic rhinitis. Objective: To evaluate and compare the efficacy of subcutaneous versus sublingual immunotherapy in treatment of allergic rhinitis. Materials and methods: Patients divided into Group A: twenty patients received subcutaneous immunotherapy and group B: twenty patients received sublingual immunotherapy for twelve months. We assessed skin prick test, symptom score and medication use, quality of life and nasal smear eosinophilic count before and after treatment. Results: In group A, clinical improvement was achieved in 100% of monosensitised and 62.5% of polysensitised patients, while in group B 100% of monosensitised and 60% of of polysensitised patients exhibited clinical improvement. Conclusion: The subcutaneous and sublingual routes of immunotherapy have similar efficacy.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior
AU  - Magdy Abdullah Sayedelahl
AU  - Naser Nagib Nasr
AU  - Mahmoud Hamed Akr
AU  - Dina Sayed Sheha
AU  - Tahany Mohamed Rabie
Y1  - 2015/07/02
PY  - 2015
N1  - https://doi.org/10.11648/j.iji.20150303.13
DO  - 10.11648/j.iji.20150303.13
T2  - International Journal of Immunology
JF  - International Journal of Immunology
JO  - International Journal of Immunology
SP  - 42
EP  - 46
PB  - Science Publishing Group
SN  - 2329-1753
UR  - https://doi.org/10.11648/j.iji.20150303.13
AB  - Background: A randomized single-blinded study including 50 patients with allergic rhinitis. Objective: To evaluate and compare the efficacy of subcutaneous versus sublingual immunotherapy in treatment of allergic rhinitis. Materials and methods: Patients divided into Group A: twenty patients received subcutaneous immunotherapy and group B: twenty patients received sublingual immunotherapy for twelve months. We assessed skin prick test, symptom score and medication use, quality of life and nasal smear eosinophilic count before and after treatment. Results: In group A, clinical improvement was achieved in 100% of monosensitised and 62.5% of polysensitised patients, while in group B 100% of monosensitised and 60% of of polysensitised patients exhibited clinical improvement. Conclusion: The subcutaneous and sublingual routes of immunotherapy have similar efficacy.
VL  - 3
IS  - 3
ER  -

Copy | Download