Introduction: Acute post streptococcal glomerulonephritis is one of the commonest causes of glomerular disease in developing countries. Ureum and creatinine examination not only can be used to support the diagnosis but also to identify and detect early organs disturbances and predict the patient prognosis. Objective: This study aims to observe the ureum and creatinine serum level in APSGN children and its relationship with the outcomes. Methods: A retrospective cohort design regarding the prognostic value of serum ureum and creatinine levels for APSGN children outcomes. The data was collected from medical records of APSGN children treated at Dr. Wahidin Sudirohusodo Hospital Makassar from 2009-2013. Results: There is no significant correlation between the outcome and sex (p=0.961), nutritional status (p=1.000), and age (p=0.108). There is a significant difference both in early ureum levels to outcome with p=0.003 and in early creatinine levels to outcome with p=0.020. There is tendency to decreased levels of ureum and creatinine serum of survival group (p=0.000) while hospitalization and trend of increased or stagnan levels of ureum and creatinine serum of non survival group while hospitalization. Multivariate analyses indicated that serum ureum levels <119 mg/dl is an independent prognostic factor for APSGN outcomes in children with p=0.032, OR 1.021, and CI 95% 1.002-1.041. Conclusion: It seems that serum ureum is an independent prognostic factor for APSGN, where serum ureum levels <119 mg/dl and creatinine levels <1.3 mg/dl have a good prognosis. Out of the 95 patients as sampled, there were 90 (94.7%) cured, and 5 (5.2%) patients died.
| Published in | American Journal of Health Research (Volume 3, Issue 3) |
| DOI | 10.11648/j.ajhr.20150303.17 |
| Page(s) | 151-155 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Acute Post Streptococcal Glomerulonephritis, Prognostic Value, Ureum, Creatinine, Child
| [1] | Iturbe BR, Musser JM. The current state of poststreptococcal glomerulonephritis. J Am Soc Nephrol. 2008; 19: 1855-64. |
| [2] | Wong W. Glomerulonephritis-acute in children. Starship Children’s Health Clinical Guideline: 2009; 1-3. |
| [3] | Mossie L, Shimelis D. Outcome of children with acute post streptococcal glomerulonephritis in Tikur Anbessa specialized teaching hospital. Ethiopian Journal of Pediatrics and Child Health. 2012; 8: 1-16. |
| [4] | Kumar GV. Clinical study of post streptococcal glomerulonephritis in children with special reference to presentation. Current Pediatric Respirology; 2011; 15(2): 89-92. |
| [5] | Bingler MA, Ellis D, Moritz ML. "Acute post-streptococcal glomerulonephritis in a 14-month-old boy: why is this uncommon?". Pediatr Nephrol. 2007; 22 (3): 448-50 |
| [6] | Suarta IK. Erythrocyturia and proteinuria conversion in post-streptococcal acute glomerulonephritis. Paediatrica Indonesiana. 2006; 46(3-4): 71-6. |
| [7] | Ahn SY, Ingulli E. Acute poststreptococcal glomerulonephritis: an update. Curr Opin Pediatr. Apr 2008; 20(2):157-62. |
| [8] | Etuk IS, Anah MU, Eyong ME. Epidemiology and clinical features of glomerulonephritis in Calabar. Niger J Physiol Sci. 2009; 24(2): 91-4. |
| [9] | Sepahi MA, Shajari A, Shakiba M. Acute glomerulonephritis: A 7 years follow up of children in Center of Iran. Acta Medica Iranica. 2011; 49(6): 375-8. |
| [10] | Ho CZ, Chen YH. The clinical analyses of acute glomerulonephritis and neprotic syndrome in Chinese children. J Med Sci. 1995; 15 (6): 429-40. |
| [11] | Albar H, Rauf S. The profile of acute glomerulonephritis among Indonesian children. Paediatrica Indonesiana; 2005; 45(11-12): 264-9. |
APA Style
Ahmad Hadiwijaya, Husein Albar, Syarifuddin Rauf, Dasril Daud. (2015). Prognostic Factor of Ureum and Creatinine Serum of Acute Post Streptococcal Glomerulonephritis in Children. American Journal of Health Research, 3(3), 151-155. https://doi.org/10.11648/j.ajhr.20150303.17
ACS Style
Ahmad Hadiwijaya; Husein Albar; Syarifuddin Rauf; Dasril Daud. Prognostic Factor of Ureum and Creatinine Serum of Acute Post Streptococcal Glomerulonephritis in Children. Am. J. Health Res. 2015, 3(3), 151-155. doi: 10.11648/j.ajhr.20150303.17
AMA Style
Ahmad Hadiwijaya, Husein Albar, Syarifuddin Rauf, Dasril Daud. Prognostic Factor of Ureum and Creatinine Serum of Acute Post Streptococcal Glomerulonephritis in Children. Am J Health Res. 2015;3(3):151-155. doi: 10.11648/j.ajhr.20150303.17
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Download@article{10.11648/j.ajhr.20150303.17,
author = {Ahmad Hadiwijaya and Husein Albar and Syarifuddin Rauf and Dasril Daud},
title = {Prognostic Factor of Ureum and Creatinine Serum of Acute Post Streptococcal Glomerulonephritis in Children},
journal = {American Journal of Health Research},
volume = {3},
number = {3},
pages = {151-155},
doi = {10.11648/j.ajhr.20150303.17},
url = {https://doi.org/10.11648/j.ajhr.20150303.17},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20150303.17},
abstract = {Introduction: Acute post streptococcal glomerulonephritis is one of the commonest causes of glomerular disease in developing countries. Ureum and creatinine examination not only can be used to support the diagnosis but also to identify and detect early organs disturbances and predict the patient prognosis. Objective: This study aims to observe the ureum and creatinine serum level in APSGN children and its relationship with the outcomes. Methods: A retrospective cohort design regarding the prognostic value of serum ureum and creatinine levels for APSGN children outcomes. The data was collected from medical records of APSGN children treated at Dr. Wahidin Sudirohusodo Hospital Makassar from 2009-2013. Results: There is no significant correlation between the outcome and sex (p=0.961), nutritional status (p=1.000), and age (p=0.108). There is a significant difference both in early ureum levels to outcome with p=0.003 and in early creatinine levels to outcome with p=0.020. There is tendency to decreased levels of ureum and creatinine serum of survival group (p=0.000) while hospitalization and trend of increased or stagnan levels of ureum and creatinine serum of non survival group while hospitalization. Multivariate analyses indicated that serum ureum levels <119 mg/dl is an independent prognostic factor for APSGN outcomes in children with p=0.032, OR 1.021, and CI 95% 1.002-1.041. Conclusion: It seems that serum ureum is an independent prognostic factor for APSGN, where serum ureum levels <119 mg/dl and creatinine levels <1.3 mg/dl have a good prognosis. Out of the 95 patients as sampled, there were 90 (94.7%) cured, and 5 (5.2%) patients died.},
year = {2015}
}
TY - JOUR T1 - Prognostic Factor of Ureum and Creatinine Serum of Acute Post Streptococcal Glomerulonephritis in Children AU - Ahmad Hadiwijaya AU - Husein Albar AU - Syarifuddin Rauf AU - Dasril Daud Y1 - 2015/04/29 PY - 2015 N1 - https://doi.org/10.11648/j.ajhr.20150303.17 DO - 10.11648/j.ajhr.20150303.17 T2 - American Journal of Health Research JF - American Journal of Health Research JO - American Journal of Health Research SP - 151 EP - 155 PB - Science Publishing Group SN - 2330-8796 UR - https://doi.org/10.11648/j.ajhr.20150303.17 AB - Introduction: Acute post streptococcal glomerulonephritis is one of the commonest causes of glomerular disease in developing countries. Ureum and creatinine examination not only can be used to support the diagnosis but also to identify and detect early organs disturbances and predict the patient prognosis. Objective: This study aims to observe the ureum and creatinine serum level in APSGN children and its relationship with the outcomes. Methods: A retrospective cohort design regarding the prognostic value of serum ureum and creatinine levels for APSGN children outcomes. The data was collected from medical records of APSGN children treated at Dr. Wahidin Sudirohusodo Hospital Makassar from 2009-2013. Results: There is no significant correlation between the outcome and sex (p=0.961), nutritional status (p=1.000), and age (p=0.108). There is a significant difference both in early ureum levels to outcome with p=0.003 and in early creatinine levels to outcome with p=0.020. There is tendency to decreased levels of ureum and creatinine serum of survival group (p=0.000) while hospitalization and trend of increased or stagnan levels of ureum and creatinine serum of non survival group while hospitalization. Multivariate analyses indicated that serum ureum levels <119 mg/dl is an independent prognostic factor for APSGN outcomes in children with p=0.032, OR 1.021, and CI 95% 1.002-1.041. Conclusion: It seems that serum ureum is an independent prognostic factor for APSGN, where serum ureum levels <119 mg/dl and creatinine levels <1.3 mg/dl have a good prognosis. Out of the 95 patients as sampled, there were 90 (94.7%) cured, and 5 (5.2%) patients died. VL - 3 IS - 3 ER -
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